Histamine release and gastric mucosal damage
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چکیده
منابع مشابه
Bile salt-induced gastric mucosal damage and histamine receptor antagonists.
The effects of both an H1 receptor antagonist and an H2 receptor antagonist on changes in monovalent ion flux induced by topical sodium taurocholate were studied in antrectomised dogs fashioned with a denervated fundic pouch. The magnitude of taurocholate-induced ion flux was unaffected by topical administration of H1 or H2 receptor antagonists Parenteral administration of H1 or H2 receptor ant...
متن کاملBile salt-induced gastric mucosal damage and histamine
The effects of both an H1 receptor antagonist and an H2 receptor antagonist on changes in monovalent ion flux induced by topical sodium taurocholate were studied in antrectomised dogs fashioned with a denervated fundic pouch. The magnitude of taurocholateinduced ion flux was unaffected by topical administration of H1 or H2 receptor antagonists. Parenteral administration of H1 or H2 receptor ant...
متن کاملDetermination of Histamine Release in Isolated Gastric Mucosal Cells Gastric mucosal cells were isolated from male Wistar rats
secretion in vivo and in vitro. The inhibitory effect of endogenous NO on stimulated acid secretion has also been demonstrated in rats. Thus, NO is generally thought to inhibit the stimulation of gastric acid secretion. On the contrary, we have demonstrated that NO has a stimulatory effect on gastric acid secretion: Sodium nitroprusside, a NO donor, increases acid secretion in isolated mouse st...
متن کاملRectal mucosal histamine release in ulcerative colitis.
1. Rectal dialysis in vivo was used to assess rectal mucosal release of histamine in patients with ulcerative colitis and in control subjects. 2. Rectal mucosal histamine release was significantly increased in ulcerative colitis, whether the patients were in remission or relapse. The highest values were found in active colitis, but in several such patients histamine release was within the contr...
متن کاملEffect of histamine on canine gastric mucosal adenylate cyclase.
The effects of histamine, Nalpha-dimethylhistamine, 4,5-methylhistamine, Ntau-methylhistamine, pentagastrin, carbachol, and NaF on the adenylate cyclase activity from canine gastric mucosa were investigated in cell-free preparations. In gastric fundic mucosa, histamine (10(-4) M), Nalpha-dimethylhistamine (10(-4) M), 4,5-methylhistamine (10(-4 M), and NaF (10)-2) M) significantly (P less than 0...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1978
ISSN: 0016-5085
DOI: 10.1016/0016-5085(78)90306-2